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Resources on What is Catatonia

Catatonia in General
Scholarly Articles

2023

Report of the clinical presentation, course, and treatment outcomes in patients presenting with secondary catatonia in a general hospital setting.

Vaidya BP et al. Indian Journal of Psychological Medicine

2023

Review of the changes in the incidence of catatonia and possible underlying causes. Recommends the establishment of an international society and a journal dedicated to the study of catatonia.

Ungvari GS et al. World Journal of Psychiatry

2023

Case report of a 20-year-old male who presented with acute onset of catatonic symptoms in the absence of any preexisting psychiatric disorder.

Singh A., Bhalla, JK.  Indian Journal of Private Psychiatry

2022

Systematic review of historical and modern German and English texts focusing on catatonic phenomena, published from 1800 to 1900.

Hirjak D et al. Schizophrenia Research

2021

Review of identification, treatment, and prevention of Catatonia. Catatonia needs to be considered whenever a person does not engage with the world.

Heckers S, Walthers S JAMA Psychiatry

2021

ECT-responsive catatonia includes neuroleptic malignant syndrome, delirious mania, self injurious behaviors in autism, and limbic encephalitis.

Fink, Max MD The Journal of ECT

2021

An overview of pathophysiology, diagnosis, treatment, complications and risk factors. Recognition that early treatment is associated with better outcomes.

Edinoff AN et al. Neurology International

2020

Catatonia is becoming more recognized clinically and in ongoing research. Unresolved is the diagnosis and treatment of catatonia in the setting of delirium.

Mormando C and Francis A. International Review of Psychiatry

2018

Catatonia is a cluster of motor features that appear in many recognized psychiatric illnesses. 80% of patients’ symptoms are relieved with benzodiazepines, and in those who fail, improvement is achieved by ECT.

Appiani FJ and Castro GS Schizophrenia Research

2018

Catatonia has frequently been reported in systemic lupus erythematosus.

.Boeke A. et al. Psychosomatics

2016

Review - Physicians should maintain high level of suspicion for catatonia in patients experiencing an acute psychiatric illness. The wide range of psychomotor abnormalities are not present in all patients. Most patients respond to lorazepam or ECT.  The use of antipsychotics should be avoided.

Rasmussen SA et al. World Journal of Psychiatry.

2016

Description of the catatonic syndrome, classification issues, clinical presentation, and suspected pathophysiology.

Walther S & Strik W. CNS Spectrums

2015

Summarizes current knowledge related to the diagnosis, epidemiology, etiology, and management of catatonia in the medically ill population.

Denysenko L et al.

2012

This review has the aim of improving early recognition and effective treatment of catatonia, critically going through its historical descriptions and revisiting its nosographical collocation in current classification systems.

Bartolommei N. et al. Journal of Psychopathology

2012

Review of the history of catatonia and it’s present status

Fink, Max. Acta Psychiatrica Scandivanica

2011

Exploratory chart review of the phenomenology, clinical profile and treatment response of subjects admitted to the psychiatry inpatient with catatonia.

Dutt A et al. Indian Journal of Psychiatry

2010

Catatonia is a distinct neuropsychiatric syndrome that is becoming more recognized clinically. Treatment with benzodiazepines or ECT leads to a dramatic and rapid response. What is the role of antipsychotic agents in treatment and potential adverse effects.

Francis A. Current Psychiatry Reports

2010

Catatonia is readily diagnosable, verifiable by a lorazepam challenge test, and rapidly treatable with high doses of lorazepam or ECT. It is time to place catatonia into its own home in the psychiatric classification.

Fink M et al. Schizophrenia Bulletin

2009

2009

History, recognition, different forms, appropriate treatments, and prevalence of catatonia.

Fink M, Taylor MA. Archives of General Psychiatry

Clinical presentation of catatonia, subtypes and differential diagnosis, neurobiology of catatonic symptoms, diagnosis, underlying cause, and various treatments.

Daniels J. The Journal of Neuropsychiatry and Clinical Neurosciences

2008

Review: Catatonia is a common neuropsychiatric syndrome characterized by the presence of various motor signs and symptoms. Classifications are based on the type of presentation and the duration of symptoms.

Weder N et al. Annals of Clinical Psychiatry

2007

Overview of catatonia, including clinical features and different types, differential diagnoses, use of rating scales, management, prognosis, and the association between catatonia and neuroleptic malignant syndrome.

Rajagopal S. Advances in Psychiatric Treatment
Books

2020

Learning About Catatonia, Neuroleptic Malignant Syndrome, and Serotonin Syndrome: A Programmed Text
Stern T (Ed) MGH Psychiatry Academy

2018

The Madness of Fear: A History of Catatonia
Shorter E & Fink M  Oxford University Press eBooks

2015

Catatonia on the Consultation Liaison Service and Other Clinical Settings
Carroll BT (Ed) and Spiegel DR (Ed) Nova Biomedical

2010

Catatonia: An Analysis and Examination of the Validity of Current Diagnostic Trends
Jinkerson J and Morris M VDM Verlag Dr. Miller

2004

Catatonia: From Psychopathology to Neurobiology
Caroff SN, Mann SC, Francis A American Psychiatric Association Publishing

2003

Catatonia:  A Clinician's Guide to Diagnosis and Treatment
Fink M & Taylor M Cambridge University Press 
Websites and Presentations

2024

Caroff S. Clinical Care Options, LLC

2023

American Academy of Child & Adolescent Psychiatry

2022

Royal College of Psychiatrists

2021

Psychology Today

2020

Celano, CM Massachusetts General Hospital Psychiatry Academy
Videos

2023

Francis, A. UNM Department of Psychiatry and Behavioral Sciences
Podcasts

2017

Psych Essentials, Episode 16
Fear

2022

The dominant theme of thoughts, feelings, and behaviors in Catatonia were overwhelming anxiety, fear, and depression.

Zingela Z et al. BMC Psychology

2021

Initial data suggests a correlation between episodes of intense fear associated with trauma (including psychological) and PTSD and some forms of catatonic responses.

Biles TR. et al. The Journal of Nervous and Mental Disease

2021

Pediatric patient had two traumatic experiences which led to catatonia. Improved with benzodiazepines and ECT.

Ahmed GK et al. Frontiers in Psychiatry

2019

Authors suggest that it would be of interest to try benzodiazepines in resignation syndrome in children seeking asylum because of the symptoms of stupor, mutism, and negativism.

von Knorring, AL & Hultcrantz, E. European Child & Adolescent Psychiatry

2017

Seeing catatonia as behaviors sustained by severe fear offers a mechanism that encourages study while applying effective treatments, and suggests the mechanism by which sedatives relieve catatonia.

Fink M.

2004

Catatonia, long viewed as a motor disorder, may be better understood as a fear response. It may represent a common “end state” response to feelings of imminent doom and can serve as a template to understand other psychiatric disorders.

Moskowitz, AK Psychological Review
Prevalence

2022

The range of prevalence ranges from less than 10% to just above 60%.  Diagnosis may be influenced by the screening tools used. 

Zingela Z et al. PLoS One

2021

Incidence of catatonia is probably an underestimate of the true incidence because most cases are not recognised by clinicians. Clinicians need to be vigilant for its presentations and cognizant of its various forms and etiologies, even in youth.

Rogers JP et al . Psychological Medicine

2021

More 1/2 of catatonic patients may go undiagnosed on admission, and 1/3 remain undiagnosed after a psychiatric consultation

Almeida M. et al. The Primary Care Companion for CNS Disorders

2021

Bush-Francis Catatonia Rating Scale has high inter-rater reliability with high correlation coefficients, while DSM-5 had deficiencies in screening for catatonia.

Zingela Z et al. International Journal of Mental Health Systems

2019

Catatonia can be seen in up to 20% of patients with autism spectrum disorders.

Beach S. & Francis A. Psychiatric Times

2018

A retrospective chart review using DSM-5 criteria to diagnose catatonia in medical inpatients between 2011 and 2013. Catatonia appears to be frequently under-diagnosed in the general hospital. 

Llesuy JR et al. The Journal of Neuropsychiatry and Clinical Neurosciences

2018

Catatonia is not infrequent in older adults in acute general medical settings. Nonpsychiatric causes of catatonia in older adults in acute general medical settings is 1/3 of all cases and associated with delirium in 50%.

Serra-Mestres J and Jaimes-Albornoz W Geriatrics

2017

Catatonia is a clinically and epidemiologically relevant condition that occurs throughout several mental and medical conditions. Its prevalence has not decreased over time and does not seem to depend on different rating scales/criteria.

Solmi M et al. Schizophrenia Bulletin

2016

Catatonia occurs in 9-17% of patients with acute psychiatric conditions. 

Rasmussen SA et al. World Journal of Psychiatry

2015

Current data supports catatonia is common and often severe. Prompt identification and treatment can produce a robust improvement in most cases. 

Wilcox JA & Duffy PR Behavioral Sciences

2009

History, recognition, different forms, appropriate treatments, and prevalence of catatonia.

Fink M & Taylor MA. Archives of General Psychiatry

2003

About 90,000 cases of catatonia occur each year in U.S. hospitals. Prevalence among psychiatric patients ranges from 7.6% to 38%.

Taylor MA & Fink M The American Journal of Psychiatry

2003

Reported prevalence of catatonia of 5.5% among new intakes at a child and adolescent psychiatry outpatient clinic.

Thakur A et al.  Australian & New Zealand Journal of Psychiatry
Post and Peripartum

2023

 Postpartum may be a period of high risk for catatonia and obstetric factors, such as birth complications, may be relevant.

Delvi A et al. Schizophrenia Research

2022

There is a need for greater awareness and additional research on catatonia during pregnancy and the postpartum period.

Csihi L et al. Schizophrenia Research
Catatonia in Older Adults

2022

Systematic literature review. Catatonia in older patients is highly prevalent and tends to have a multifactorial etiology. Symptomatic treatment is safe and effective.

Jaimes-Albornoz W et al. World Journal of Psychiatry

2018

Catatonia is not infrequent in older adults in acute general medical settings. Clinicians should have an increased awareness of catatonia to implement appropriate treatment.

Serra-Mestres J & Jaimes-Albornoz W Geriatrics
Catatonia in Children and Adolescents

2023

Three cases to illustrate the presentation, diagnostic evaluation, varied etiology, and management of catatonia in adolescents.

Gupta M et al. International Journal of Academic Medicine and Pharmacy

2023

Examination of the influence of age on potential drug safety signals of catatonia among the pediatric population.

Merino D et al. European Child & Adolescent Psychiatry

2022

Three pediatric patients where catatonia was erroneously attributed to existing pathologies that lead to a prolonged disease state. More rigorous education will improve recognition and treatment of catatonia.

Reinfeld S & Gill P CNS Spectrums

2022

Catatonia is rarely diagnosed in pediatric patients in general hospitals but is associated with significant and severe psychiatric and medical comorbidities.

Luccarelli J et al. Frontiers in Psychiatry

2022

Catatonia in a 16-year-old male with first onset psychosis successfully managed with lorazepam and clozapine. Engaging effectively with patient's family is important to identify and manage catatonia in children.

Vargas JG et al. Psychiatry Research Case Reports

2020

Review of the literature on catatonia, focusing on children and adolescents. 

Remberk B et al. Psychiatria Polska

2018

Advances in child and adolescent catatonia research have offeredimprovements in understanding catatonia and in new therapeutic opportunities. It's important to direct patients to centers that have developed specific expertise.

Benarous X et al. Schizophrenia Research

2018

Pediatric catatonia is potentially lethal yet can be effectively treated if accurately identified early in its course. It should be regularly considered by all clinicians who care for children and adolescents.

Sorg EM et al. Psychosomatics

2016

Resignation syndrome (RS) is a long-standing disorder affecting psychologically traumatized children and adolescents in the midst of a strenuous and lengthy migration process. RS should be perceived as catatonia is a hypothesis that should be tested.

Sallin K et al.  Frontiers in Behavioral Neuroscience

2012

Catatonia is frequently missed among children and adolescents receiving psychiatric treatment and are not receiving effective treatments. Agitated forms of catatonia (with aggression) are common among a subgroup of psychiatric patients who are at a higher risk.

Ghaziuddin N et al. Acta Psychiatrica Scandinavica

2012

Catatonia in children and adolescents is associated with a high prevalence of medical conditions. Not acknowledging this may greatly delay the diagnosis of medically related catatonia and deny patients treatment opportunities.

Consoli A et al. Schizophrenia Research

2012

The literature supports the view that deprivation, abuse, and trauma can precipitate catatonia in children and adolescents.  Catatonic symptoms may be falsely attributed to other disorders or syndromes.

Dhossche DM et al. Acta Psychiatrica Scandinavica

2010

Pediatric catatonia may be underdiagnosed. Current diagnostic criteria of catatonia in children and adolescents diagnosed with childhood disintegrative disorder, Kleine-Levin syndrome, Prader-Willi syndrome, tic disorder, and autoimmune encephalitis.

Dhossche DM & Wachtel LE Pediatric Neurology

2010

Catatonia is a treatable syndrome. It occurs in children and adolescents as well as adults.  Benzodiazepines and ECT are effective treatments for children, adolescents, and adults. These findings suggest that catatonia should be an independent category in psychiatric classification.

Dhossche DM et al.  Primary Psychiatry

2009

Catatonia is one of the most severe psychiatric syndromes in adolescents and associated with a 60-fold increased risk of premature death, including suicide, when compared to the general population of same sex and age.

Cornic F et al. Schizophrenia Research 

2008

Literature review of all the cases of organic catatonia in children and adolescents from January 1969 to June 2007. Catatonic syndromes can be observed in children and adolescents in association with organic diseases.

Lahutte B et al. Progress in Neuro-psychopharmacology & Biological Psychiatry

2003

Incidence and phenomenology of catatonia in a child and adolescent population.

Thakur A et al.  Australian & New Zealand Journal of Psychiatry

2002

Literature review: Catatonia is not rare in child and adolescent populations. Clinicians should evaluate for its presence using rating scales and medical examination. If suspected, the lorazepam challenge should be considered an invaluable tool for confirming its presence.

Takaoka K & Takata T Psychiatry and Clinical Neurosciences
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